After many months of closely watched negotiations, the Centers for Medicare & Medicaid Services (CMS) announced the list of negotiated prices for 10 drugs. This marks the first set of negotiations between Medicare and drug makers taking place as part of the Inflation Reduction Act, which President Joe Biden signed into law in 2022.

“Americans pay too much for their prescription drugs. That makes todays announcement historic,” Department of Health and Human Services (HHS) Secretary Xavier Becerra said in a CMS press release.

The 10 drugs Medicare negotiated prices for include blockbusters Jardiance, Stelara and Eliquis. The drugs treat diabetes, heart failure, arthritis and more, and the negotiated prices are as much as 79% lower than their prices in 2023. The negotiated prices apply for people with Medicare Part D prescription drug coverage.

The Biden White House said the negotiated prices will save taxpayers an estimated $6 billion, and people enrolled in Medicare with Part D prescription drug coverage are expected to save $1.5 billion in out-of-pocket costs. The Congressional Budget Office estimates Medicare will save $100 billion over the next 10 years thanks to these negotiations.

The list of Medicare negotiated drug prices

Medicare announced the 10 drugs it chose to negotiate prices for last year. Those drugs were Eliquis, Jardiance, Xarelto, Januvia, Farxiga, Entresto, Enbrel, Imbruvica, Stelara and Fiasp/NovoLog.

CMS is following a certain set of parameters to determine which drugs are eligible for negotiations, which includes when the drugs were approved by the FDA and what they treat. After narrowing down a list of drugs eligible for negotiation under the parameters, Medicare further narrowed down the list to these 10 drugs based on which had the highest Medicare Part D expenditures.

These are the negotiated prices, noting that each price is for a 30-day supply:

Eliquis:

Jardiance

Xarelto

Januvia

Farxiga

Entresto

Enbrel

Imbruvica

Stelara

Fiasp/NovoLog

When do the Medicare drug prices go into effect?

These negotiated drug prices will go into effect for Medicare Part D recipients on Jan. 1, 2026. Approximately 10 million Medicare enrollees used this set of 10 drugs in 2023 (combined), so it’s expected the lower prices will have a wide impact.

Along with these drug prices, Part D recipients will soon see other changes in prices. Starting in 2025, they will have a $2,000 cap on out-of-pocket costs, also as part of the Inflation Reduction Act. This is one of the Medicare changes coming in 2025, and the cap could change after 2025.

What’s next for Medicare drug price negotiations?

This marks just the first set of Medicare drug price negotiations. Next year, Medicare will select up to 15 more drugs to negotiate for Part D recipients. The following year, 2026, Medicare will select another up to 15 drugs to negotiate, and that will be for drugs covered under Part D or Part B.

The plan is for Medicare to continue to negotiate up to 20 drugs every year after 2026.

“We applaud this monumental milestone in curbing rising drug prices and helping older adults afford their medications while reducing costs for taxpayers,” the Medicare Rights Center said about the announcement of the first set of negotiated prices. “The effect of these negotiations will build upon itself year after year as more and more drugs have prices that better reflect their value.”

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