Christina Applegate was still recovering from her first run-in with COVID-19 when another virus recently had her health in the toilet again.

The "Dead to Me" star spoke humorously — and graphically — about her "gross" experience with a sapovirus infection in the sixth episode of "MesSy," the multiple sclerosis-themed podcast she shares with actor Jamie-Lynn Sigler.

"It's now time for the poop talk," Sigler introduced the segment.

"It's a poop pod," Applegate said. "If you don't like this part, totally fine. I get it."

It started with dizzy spells and a bout of uncontrollable diarrhea.

"I couldn't eat. I couldn't anything," Applegate said, so she took a stool test. "You poop into a receptacle, and then you have to scoop your own poop into vials. And it was so gross, I started vomiting whilst doing this."

The test told her she had contracted sapovirus, which occurs when one person ingests another's fecal matter, most often via contaminated food. According to the National Institutes of Health, "Sapovirus infections are responsible for both sporadic cases and occasional outbreaks of acute gastroenteritis."

The culprit, Applegate said, was most likely a takeout salad from a vegan restaurant she's visited for years and declined to name.

"They say that it's mostly from salads because cooked food kind of kills the bacteria," she said. "Someone else's poop went into my mouth, and I ate it."

As if the virus wasn't bad enough, Applegate said it exacerbated the symptoms of her multiple sclerosis, with which she was diagnosed in 2021. According to Johns Hopkins Medicine, the chronic illness can cause trouble walking, difficulty with balance and fatigue.

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